(via Boing Boing) ArsTechnica has a post up about scientific fraud, by way of explaining how to do it. It follows the successes and errors (mostly successes) of Dr. Yoshitaka Fujii, who was publishing papers based on fabricated data for about 20 years before he was formally caught.
The article goes on to offer 8 tips on how to defraud the scientific institution:
05. Don't publish in journals focused on your field. In general (see point 4), it's best to avoid publishing in high-profile journals altogether, since those will draw attention to your work. At the same time, you don't want to keep seeing your stuff published in the same journals, or those editors will start feeling a personal responsibility to make sure their star researcher is on the up-and-up.
It seems to me that the biggest flaws in science revolve around the pride of individual scientists and institutions. There's no easy solution to that -- unlike government, I don't think a ground-up deconstruction and reassembly of science would work. But to start, the article references huge stigma around even trying to uncover fraud. Adding a system of random investigations of scientists irrespective of reputation might help open up suspicious scientists to exposure.